hif-1 inhibitor-5 — TargetMol Chemicals

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Search Results for " hif-1 inhibitor-5 "

Compounds

Cat No.	Product Name	Targets
T74804	HIF-1 inhibitor-5
	HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1].
T13050	SYP-5	HIF/HIF Prolyl-Hydroxylase , HIF
	SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.	HIF/HIF Prolyl-Hydroxylase , HIF
T61614	HIF-2α-IN-5
	HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].
T60532	HIF-1α-IN-5
	HIF-1α-IN-5 is an inhibitor of HIF-1α with an IC 50 value of 24 nM in HEK293T cells that also inhibits the activity of MAO-A. HIF-1α-IN-5 downregulates the mRNA expressions of VEGF and PDK1 under hypoxia. HIF-1α-IN-5 has...
T74530	GEM-5
	GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and c...